Salazar-Enciso R, Guerrero-Hernández A, Gómez AM, Benitah JP, Rueda A. Aldosterone-Induced Sarco/Endoplasmic Reticulum Ca2+ Pump Upregulation Counterbalances Cav1.2-Mediated Ca2+ Influx in Mesenteric Arteries. Frontiers in Physiology (2022) 13:834220.
doi: 10.3389/fphys.2022.834220
Gaitán-González P, Sánchez-Hernández R, Arias-Montaño JA, Rueda A. Tale of two kinases: Protein kinase A and Ca2+/calmodulin-dependent protein kinase II in pre-diabetic cardiomyopathy. World Journal of Diabetes (2021); 12(10):1704-1718.
doi: 10.4239/wjd.v12.i10.1704
Val-Blasco A, Gil-Fernández M, Rueda A, Pereira L, Delgado C, Smani T, Ruiz Hurtado G, Fernández-Velasco M. Ca2+ mishandling in heart failure: potential targets. Acta Physiol (Oxf) (2021) 232(3):e13691.
doi: 10.1111/apha.13691
Espadas-Álvarez H, Romero-García T, Rosenbaum T, Rueda A, García-Villegas R. TRPV4 activity regulates nuclear Ca2+ and transcriptional functions of β‐catenin in a renal epithelial cell model. Journal of Cellular Physiology (2021) 236(5):3599-3614.
doi: 10.1002/jcp.30096
Gil-Fernández M, Navarro-García JA, Val-Blasco A, González-Lafuente L, Martínez JC, Rueda A, Tamayo M, Morgado JL, Zaragoza C, Ruilope LM, Delgado C, Ruiz-Hurtado G, Fernández-Velasco M. Genetic Deletion of NOD1 Prevents Cardiac Ca2+ Mishandling Induced by Experimental Chronic Kidney Disease. Int J Mol Sci. (2020) 21(22):8868.
doi: 10.3390/ijms21228868
Romero-García T, Landa-Galván HV, Pavón N, Mercado-Morales M, Valdivia HH, Rueda A. Autonomous activation of CaMKII exacerbates diastolic calcium leak during beta-adrenergic stimulation in cardiomyocytes of metabolic syndrome rats. Cell Calcium (2020) 91: 102267.
doi: 10.1016/j.ceca.2020.102267
Navarro-García JA, Rueda A, Romero-García T, Aceves-Ripoll J, Rodríguez-Sánchez E, González-Lafuente L, Zaragoza C, Fernández-Velasco M, Kuro-O M, Ruilope LM, Ruiz-Hurtado G. Enhanced Klotho availability protects against cardiac dysfunction induced by uraemic cardiomyopathy by regulating Ca2+ handling. Br J Pharmacol. (2020) Aug 24.
doi: 10.1111/bph.15235
Ruíz-Hurtado G, Rueda A, Pereira L, Fernández-Velasco M. Editorial: Evolving Picture of Calcium Handling in Cardiac Disease. Front. Physiol (2020) 11:1013.
doi: 10.3389/fphys.2020.01013
Landa-Galván HV, Ríos-Castro E, Romero-García T, Rueda A, Olivares-Reyes JA. Metabolic syndrome diminishes insulin-induced Akt activation and causes a redistribution of Akt-interacting proteins in cardiomyocytes. PLoS ONE (2020) 15(1): e0228115.
doi: 10.1371/journal.pone.0228115
Fernández-Miranda G, Romero-García T, Barrera-Lechuga TP, Mercado-Morales M, Rueda A. Impaired Activity of Ryanodine Receptors Contributes to Calcium Mishandling in Cardiomyocytes of Metabolic Syndrome Rats. Front. Physiol. (2019) 10:520;
doi: 10.3389/fphys.2019.00520
Márquez MF, Totomoch-Serra A, Rueda A, Avelino-Cruz JE, and Gallegos-Cortez A. Basic and clinical insights in catecholaminergic (familial) polymorphic ventricular tachycardia. Revista de Investigación Clínica (2019) 71:217-227;
doi: 10.24875/RIC.19002939
Salazar-Enciso R, Camacho-Concha NA, Mesquita TR, Falcón D, Benitah J, Gómez AM, Rueda A. Mineralocorticoid Receptor in Calcium Handling of Vascular Smooth Muscle Cells. Calcium and Signal Transduction John N. Buchholz and Erik J. Behringer, IntechOpen. (October 24th 2018);
doi: 10.5772/intechopen.79556
Mesquita TR, Auguste G, Falcón D, Ruiz-Hurtado G, Salazar-Enciso R, Sabourin J, Lefebvre F, Viengchareun S, Kobeissy H, Lechène P, Nicolas V, Fernández-Celis A, Lauton-Santos S, Morel E, Rueda A, López-Andrés N, Gómez AM, Lombès M, Benitah JP. Specific activation of the alternative cardiac promoter of Cacna1c by the mineralocorticoid receptor. Circ Res. (2018): 122(7):e49-e61;
doi: 10.1161/CIRCRESAHA.117.312451
De Alba-Aguayo DR, Pavón N, Mercado-Morales M, Miranda-Saturnino M, López-Casamichana M, Guerrero-Hernández A, Rueda A. Increased calcium leak associated with reduced calsequestrin expression in hyperthyroid cardiomyocytes. Cell Calcium. (2017); 62:29-40;
doi: 10.1016/j.ceca.2017.01.009
Fernández-Velasco M, Ruiz-Hurtado G, Gómez AM, Rueda A. Calcium handling alterations and vascular dysfunction in diabetes. Cell Calcium. (2014); 56(5): 397-407;
doi: 10.1016/j.ceca.2014.08.007
Pereira L, Ruiz-Hurtado G, Rueda A, Mercadier JJ, Benitah JP, Gómez AM. Calcium signaling in diabetic cardiomyocytes. Cell Calcium. (2014); 56(5): 372-380;
doi: 10.1016/j.ceca.2014.08.004
Rueda A, de Alba-Aguayo DR, Valdivia HH. Ryanodine receptor, calcium leak and arrhythmias. Arch Cardiol Mex. (2014); 84(3):191-201.
Gayathri N, de Alba-Aguayo DR, Mondragón-Flores R, González-Pozos S, Miranda-Saturnino MJ, Sridharan M, Rueda A. Acute administration of chitosan nanoparticles increases calcium leak in rat cardiomyocytes. J Nano Res. (2014); 28: 29-38.
Guerrero-Hernández A, Ávila G, Rueda A. Ryanodine receptors as leak channels. Eur J Pharmacol. (2014); 739: 26-38.
Rueda A, Fernández-Velasco, M, Benitah JP, Gómez AM. Abnormal Calcium Spark/STOC Coupling in Cerebral Artery Smooth Muscle Cells of Obese Type 2 Diabetic Mice. PLoS ONE. (2013) 8(1): e53321;
doi: 10.1371/journal.pone.0053321
Fernández-Velasco M, Ruiz-Hurtado G, Rueda A, Neco P, Mercado-Morales M, Delgado C, Napolitano C, Priori SG, Richard S, Gómez A, Benitah JP. RyR calcium Leak Limits Cardiac Calcium Window Current Overcoming the Tonic Effect of Calmodulinin Mice. PLOS ONE (2011) 6:e20863.
Gómez AM, Rueda A, Sainte-Marie Y, Pereira L, Zissimopoulos S, Zhu X, Schaub R, Perrier E, Perrier R, Latouche C, Richard S, Picot MC, Jaisser F, Lai FA, Valdivia HH, Benitah JP. Mineralocorticoid modulation of cardiac ryanodine receptor activity as associated with downregulation of FK506-binding proteins. Circulation (2009) 119:2179-2187.
Fernández-Velasco M, Rueda A, Rizzi N, Benitah JP, Colombi B, Napolitano C, Priori SG, Richard S, Gómez AM. Increased Ca2+ sensitivity of the ryanodine receptor mutant RyR2R4496C underlies catecholaminergic polymorphic ventricular tachycardia. Circulation Research (2009) 104:201-209.
Franceschini S, Ilari A, Verzili D, Zamparelli C, Antaramian A, Rueda A, Valdivia HH, Chiancone E, Colotti G. Molecular basis for the impaired function of the natural F112L sorcin mutant: X-ray crystal structure, calcium affinity, and interaction with annexin VII and the ryanodine receptor. FASEB J (2008) 22:295-306.
Rueda A, Song M, Toro L, Stefani E, Valdivia HH. Sorcin modulation of calcium sparks in rat vascular smooth muscle cells. J Physiol (2006) 576:887-901.
Rueda A, Valdivia HH. Sorcin, an emergent modulator of ryanodine receptors in smooth muscle. J Mol Cell Cardiol (2004) 37: 152.
Farrell FE, Antaramian A, Rueda A, Gómez AM, Valdivia HH. Sorcin inhibits calcium release and modulates excitation-contraction coupling in the heart. J Biol Chem (2003) 278: 34660-34666.
Rueda A, García L, Guerrero-Hernández A. Luminal calcium and the activity of sarcoplasmic reticulum calcium pumps modulate histamine-induced all-or-none calcium release in smooth muscle cells. Cellular Signalling (2002) 14: 517-27.
Rueda A, García L, Soria-Jasso LE, Arias-Montaño JA, Guerrero-Hernández A. The initial inositol 1,4,5-trisphosphate response induced by histamine is strongly amplified by calcium release from internal stores in smooth muscle. Cell Calcium (2002) 31: 161-173.